Proceedings of the National Academy of Sciences, Volume 122, Issue 52, December 2025. SignificanceWe show through tryptophan fluorescence that lipid-packing defects (low lipid-packing density) are required for α-synuclein–membrane insertion, while net negative charge is not. We additionally find that on lower defect membranes, the bound …
Observations from the Little Bunker
Last updated: January 27, 2026 06:22 PM
Atmospheric CO₂
428.6 ppm
+17.4
ppm/year
Atmospheric CH₄
1940.59 ppb
+-0.24
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year